At the moment, There are 2 styles of scientific studies on itaconate: Irg1−/− macrophages and also the regulatory outcome of itaconate derivatives. These two effects have been complementary and revealed that the regulatory mechanisms of itaconate concerned alkylation on Keap1 to activate Nrf2, succinate dehydrogenase inhibition, activating transcription factor 3 https://lennyi665wis8.kylieblog.com/profile